Botox® Dysport® Xeomin® These quick, effective, nonsurgical treatments work by relaxing facial muscles and reduce or smooth away Frownlines, Crow’s feet wrinkles and Forehead Lines. Botox® Cosmetic, Dysport® and Xeomin® are all FDA approved for cosmetic use to treat wrinkles. Botox® brand is more popular in America. Dysport® is the number one neurotoxin used in Europe and South America. Xeomin® has no additives. Studies indicate all are safe, show similar outcomes with very subtle differences. Dr. Bartels has been injecting Botox® since 2002 and treats patients based on the individual and his experience with each product.